Comparison of the efficacy between immunomodulator drugs in moderate to severe Dry eye
Not Applicable
Completed
- Conditions
- Health Condition 1: H188- Other specified disorders of cornea
- Registration Number
- CTRI/2022/01/039630
- Lead Sponsor
- Regional Institute of Ophthalmology Kolkata
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
1. Patients with Dry eye symptoms such as Discomfort, Fatigue and Gritty sensation
2. Schirmer’s Test <10mm in 5 minutes
3. TBUT <10 sec
4. OSDI score > 15
5. Presence of Punctate staining in the Fluorescence staining of the cornea, NEI score > 3
Exclusion Criteria
1. Previous Eye Surgery
2. Use of ocular medication other than tear substitutes.
3. Contact lens wearer
4. Glaucoma patients
5. Pregnant or Lactating Mothers
6. Presence of any microbial infection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the improvement of OSDI score, schirmer I score, TBUT and NEI score in both groupTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method To assess the improvement the dry eye state of the symptomatic patients.Timepoint: 6 months;To assess the symptomatic improvement of dry eye disease patients with the above treatments.Timepoint: 6 months;To assess the visual outcome after the treatment.Timepoint: 6 months;To study prospectively the epidemiological scenario of dry eye in eastern India.Timepoint: 6 months