Study on Common Bacteria Found in Urine Samples and How They Respond to Antibiotic Treatment in Patients with Urinary Tract Infections

Not yet recruiting

Brief Summary: *Spectrum of Bacterial Isolates from Urine Samples and Their Antibiotic Sensitivity Patterns*

This study aims to identify the common bacterial pathogens causing urinary tract infections (UTIs) and to analyze their antibiotic sensitivity patterns. Midstream urine samples collected from patients aged 1 year and above with suspected UTIs will be cultured and tested for antimicrobial susceptibility. The research will focus on determining the prevalence of specific bacterial species and their resistance profiles to commonly prescribed antibiotics. The findings will help update local antibiogram data, support evidence-based empirical treatment, and promote rational antibiotic use, ultimately aiding in the management of UTIs and combating antimicrobial resistance in both community and hospital settings.

Recruitment & Eligibility

Inclusion Criteria

Patients aged 1 year and above, of all genders 2.
Patients presenting with clinical symptoms suggestive of urinary tract infection such as burning micturition, urgency, frequency, lower abdominal pain, or fever 3.
Midstream clean-catch urine samples submitted for culture and antibiotic sensitivity testing 4.
Both outpatients and inpatients from various hospital departments 6.
Patients who have not received antibiotics within the previous 48 to 72 hours before urine sample collection.

Exclusion Criteria

Patients below 1 year of age 2.
Urine samples that are contaminated, improperly labeled, or inadequately collected 3.
Repeat or duplicate urine samples from the same patient during the same episode 4.
Urine samples with polymicrobial growth (more than two organisms) unless considered under a specific sub-analysis 5.
Patients with chronic urinary catheterization or known structural urinary tract abnormalities, unless studied as a separate group 6.
Patients who have received antibiotic treatment within 48–72 hours prior to sample collection.

Primary Outcome Measures

Name	Time	Method
Identification of Predominant Bacterial Pathogens	1 year
Analyze the susceptibility patterns of the isolated organisms to commonly used antibiotics (e.g., nitrofurantoin, ciprofloxacin, ceftriaxone, amikacin, imipenem).	1 year
Determine the prevalence of multi-drug resistant (MDR) organisms.	1 year
Determine the most common bacterial species isolated from urine samples (e.g., Escherichia coli, Klebsiella spp., Proteus spp., Pseudomonas aeruginosa, Enterococcus spp., etc.).	1 year
Antibiotic Sensitivity Profiles	1 year

Secondary Outcome Measures

Name	Time	Method

Locations (1): School of Allied Health Sciences, Galgotias university
🇮🇳
Nagar, UTTAR PRADESH, India
School of Allied Health Sciences, Galgotias university
🇮🇳Nagar, UTTAR PRADESH, India
Dr Chandrasekar M
Principal investigator
8015185002
shekarmlt09@hotmail.com