Effects of an Oxymizer Versus Conventional Nasal Cannula on Endurance Time in Patients With Chronic Obstructive Pulmonary Disease IV (COPD) or Interstitial Lung Disease (ILD)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 67
- 试验地点
- 1
- 主要终点
- Difference between Endurance time with Oxymizer and conventional nasal cannula
研究概览
简要总结
The Oxymizer pendant® is a special oxygen cannula that can be used to supply high flow long term oxygen therapy. It is compatible with a wide variety of oxygen sources. In a reservoir, the Oxymizer® stores pure oxygen so that the concentration of inhaled oxygen is increased.
The aim of this study is to investigate the potential benefit of the Oxymizer® with regard to the blood oxygenation during exercise testing. Given that the "endurance time" is very sensitive for little changes in exercise capacity, this test will be used to show the difference between the Oxymizer® and a conventional nasal cannula regarding exercise duration at 70% of peak Watt and oxygenation.
The tests will be accompanied by blood gas analysis, partial pressure of carbon dioxide and heart rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •interstitial lung disease
- •long-term oxygen therapy with oxygen flow rate >= 2 L/min
排除标准
- •acute cardial decompensation
- •usual kontraindication for exposure test (higher-grad Hypertension (arterial and pulmonal), cardiac valve vitien, instabile angina pectoris, cardiac arrhythmia)
研究组 & 干预措施
Oxymizer
Using first the Oxymizer and 24 h later the conventional nasal cannula.
干预措施: Oxymizer (Device)
nasal cannula
Using first the conventional nasal cannula and 24 h later the Oxymizer
干预措施: conventional nasal cannula (Device)
结局指标
主要结局
Difference between Endurance time with Oxymizer and conventional nasal cannula
时间窗: From starting until stopping cycling, up to 60 minutes
次要结局
- Difference in oxygen saturation with Oxymizer and with conventional nasal cannula(stopping cycling, up to 60 minutes)
- Difference in PaCO2 with Oxymizer and with conventional nasal cannula(Stopping cycling, up to 60 minutes)
研究者
Klaus Kenn
Head physician (department of pneumology)
Schön Klinik Berchtesgadener Land