Clinical Outcomes of Immediate Implant Placement and Early Implant Placement

Not Applicable

• Conditions: Tooth Diseases; Tooth Fractures
• Interventions: Procedure: tooth extraction; Procedure: Implant placement; Procedure: Bone augmentation; Procedure: Coronally repositioned flap

• Registration Number: NCT04029324
• Lead Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Brief Summary

Immediate implant placement (IIP) has been an attractive treatment concept for both patients and clinicians due to reduced surgical interventions and total treatment span. Although soft-tissue alterations or midfacial recession have been demonstrated in previous studies, recent studies have reported positive result following IIP with the modification of surgical interventions. However, high-quality evidence (≥Ib: evidence from at least one randomized controlled trial) on comparing the clinical outcome of IIP with early implant placement (type 2) is limited.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-07-07
• Study Start: 2019-07-15
• Study First Submitted QC: 2019-07-22
• Study First Posted: 2019-07-23
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-22
• Last Update Posted: 2021-01-25
• Primary Completion: 2021-12-01
• Study Completion: 2022-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• age ≧18 years
• single hopeless teeth in anterior maxilla
• enough apical bone volume to achieve primary stability (>4mm)

Exclusion Criteria

• active periodontoal infection
• incomplete buccal bone plate
• unwilling to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Immediate implant placement	Implant placement	Implants are placed immediately after extraction
Immediate implant placement	Bone augmentation	Implants are placed immediately after extraction
Early implant placement	tooth extraction	Implants are placed 4-8 weeks after extraction
Immediate implant placement	tooth extraction	Implants are placed immediately after extraction
Early implant placement	Bone augmentation	Implants are placed 4-8 weeks after extraction
Early implant placement	Implant placement	Implants are placed 4-8 weeks after extraction
Early implant placement	Coronally repositioned flap	Implants are placed 4-8 weeks after extraction

Primary Outcome Measures

Name	Time	Method
Midfacial recession	1-year follow-up	Recession of midfacial gingival level before extraction and 1-year follow-up

Secondary Outcome Measures

Name	Time	Method
Probing depth	T2:crown delivery, T3: 1-year follow-up	Probing depth between crown delivery and 1-year follow-up
Bleeding on probing %	T2:crown delivery, T3: 1-year follow-up	Bleeding on probing % between crown delivery and 1-year follow-up
Visual Analogue Scale assessement	T1: immediately after surgery,T2:crown delivery, T3: 1-year follow-up	Visual Analogue Scale on post-operative pain, esthetics and function
Pink esthetic score	T2:crown delivery, T3: 1-year follow-up
Papillae recession	1-year follow-up	Recession of papillae before extraction and 1-year follow-up
marginal bone loss	1-year follow-up	marginal bone level between crown delivery and 1-year follow-up

Trial Locations

Locations (1)

Shanghai NinthPeoples' Hospital; 🇨🇳 Shanghai, China