Clinical observation of Wumei formula granules regulating Glu/GABA-Gln metabolic circuit and HPA axis in the treatment of insomnia in Jueyin syndrome
- Conditions
- insomnia
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Aged 18-70 years old;
2. Meet the diagnostic criteria of traditional Chinese medicine and the diagnostic criteria of western medicine for insomnia;
3. Sign the informed consent and voluntarily join the clinical research observation;
4. Be able to understand the research content and have normal communication and comprehension skills;
5. Have not used related drugs for the treatment of insomnia, including traditional Chinese medicine, proprietary Chinese medicine and western medicine in the past 1 week.
1. Those who are allergic to umeboshi formula granules;
2. Exclude organic brain diseases: such as Parkinson's, dementia, cerebrovascular disease, etc.: exclude insomnia caused by organic diseases: such as restless legs syndrome, periodic limb movements, OSAS, parasomnia, hypothyroidism, Hyperthyroidism, alcohol dependence, etc.
3. There are obvious systemic pain, fever and infection and other diseases;
4. Patients with insomnia due to obvious environmental interference or due to alcohol, coffee, drug dependence or mental disorders;
5. Those who are currently taking drugs that affect sleep structure.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method adrenocorticotropic hormone;GABA;cortisol hormone;Glutamate;
- Secondary Outcome Measures
Name Time Method