Clinical Study of Xiaobai Recipe Granules on Treatment of proteinuria in the patients with Chronic Glomerulonephritis (CKD1-2 stage)

Phase 1

• Conditions: Chronic Glomerulonephritis CKD1-2

• Registration Number: ITMCTR2000003397
• Lead Sponsor: Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. 160 patients with primary chronic glomerulonephritis had typical clinical symptoms of chronic nephritis, which met the western medicine diagnostic criteria of chronic nephritis.
2. The syndrome differentiation of traditional Chinese medicine belongs to the type of deficiency of spleen and kidney qi, and dampness heat and stasis;
3. Patients with chronic kidney disease (CKD) stage 1-2, GFR >= 60ml / min / 1.73m2;
4. Patients aged 18-65;
5. Effective control of hypertension (blood pressure 130-100 / 80-60mmhg);
6. Patients whose blood potassium is within the normal range;
7. 2.5g/24h >= 24h urinary protein >= 0.5g/24h;
8. Patients who sign informed consent.

Exclusion Criteria

1. Patients diagnosed as acute nephritis after infection or patients with renal damage due to essential hypertension;
2. In the past three months, western medicine glucocorticoid, immunosuppressant and Tripterygium wilfordii have been used in patients with chronic nephritis;
3. Pregnant or preparing pregnant and lactating women;
4. Patients with chronic nephritis not caused by primary kidney disease;
5. Patients who are known to be allergic to such drugs, patients with psychosis, and patients who cannot cooperate;
6. Patients who are participating in clinical trials of other drugs or who have participated in other clinical trials within 3 months.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tongue image;Pulse condition;physical examination;TCM syndrome integral;