Evaluation of intense pulsed light therapy for dry eye relief

Not Applicable

Completed

• Conditions: Meibomian gland dysfunction; Evaporative dry eye; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12616000667415
• Lead Sponsor: The University of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-23
• Study Completion: 2017-12-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 87

Inclusion Criteria

Participants with symptomatic dry eye caused by meibomian gland dysfunction.

Exclusion Criteria

Contraindications to light therapy e.g. clinical skin treatments within last two months, implants beneath the lower eyelid area, tattoos, semi-permanent make-up, or pigmented lesions in the treatment area will also be excluded from the study. Contact lens wearers must refrain from wearing contacts within one week of commencing the study, and during the study. Individuals taking prescribed photosensitising medications such as doxycycline within 3 months of study commencement.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in non-invasive tear breakup time as measured by the Oculus Keratograph 5M.[Baseline, then on Day 15, Day 45, Day 75 and Day 105 after intervention commencement];Change in lipid layer thickness as graded from interference patterns observed on imaging by the Oculus Keratograph 5M.[Baseline, then on Day 15, Day 45, Day 75 and Day 105 after intervention commencement.];Change in Symptom Assessment in Dry Eye (SANDE) questionnaire score, which comprises of two questions that use a 100 mm horizontal linear visual analogue scale to quantify both severity and frequency of dry eye symptoms.[Baseline, then on Day 15, Day 45, Day 75 and Day 105 after intervention commencement.]