Application of proteomics to aid biomarker discovery in smear positive patients of P.vivax and P.falciparum malaria
Not Applicable
- Registration Number
- CTRI/2010/091/000451
- Lead Sponsor
- Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT), Powai, Mumbai- 400 076
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1. Patients of either sex, aged 18-65 years both inclusive
2. Patients with P. vivax or P. falciparum parasitemia more than 1000 parasites/microliter
3. Those willing to provide written informed consent and comply with protocol requirements
Exclusion Criteria
1. Patients with history of significant systemic diseases like autoimmune disorders, chronic liver diseases, psychiatric illness and bleeding disorders etc. as judged by history and physical examination.
2. Severe/complicated malaria as per WHO criteria
3. Subjects unwilling to consent for the study
4. Malaria patients having mixed infection (both P.vivax and P.falciparum) in peripheral smear
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the proteomics profile of P.vivax versus P. falciparum malariaTimepoint: 6 months;To obtain the global proteome profile of P. falciparum and P.vivaxTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method ilTimepoint: Nil