The therapeutic effect of Zhu's Tiaojing Cuyun Recipe on infertility due to decreased ovarian reserve: a prospective, randomized, double-blind, controlled clinical research
Not Applicable
- Conditions
- Infertility Due to Decreased Ovarian Reserve
- Registration Number
- ITMCTR2000003691
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
(1) Women aged from 22 to 40 with normal development;
(2) In line with the Western diagnostic criteria and irregular menstruation syndrome of kidney deficiency syndrome; (3) The patient voluntarily accepts the experiment and can persist in treatment.
Exclusion Criteria
(1) Congenital uterine malformations;
(2) There are uncured endometrial diseases;
(3) Bilateral hydrosalpinx;
(4) Combined with serious medical and surgical diseases, including diabetes, hypertension, thyroid disease, etc.;
(5) Patients who are unable to correctly understand and answer the questionnaire, such as patients with severe mental illness, patients with hearing, speaking, reading and writing disorders.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pregnancy rate;
- Secondary Outcome Measures
Name Time Method reactive oxygen species, ROS;FSH;E2;phosphatidylinositol-3-kinase, PI3K;AMH;proteinkinase B, AKT;nuclear factor erythroid 2-related factor 2, Nrf2;receptor for advanced glycation end products, RAGE;advanced glycation end products, AGEs;Superoxide dismutase, SOD;Number of antral follicles;high mobility group protein box 1, HMGB1;