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Clinical Trials/NCT06540586
NCT06540586
Completed
N/A

Evaluation of the Postoperative Analgesic Efficacy of Modified Thoracoabdominal Plane Block With Perichondral Approach and Quadratus Lumborum Block in Laparoscopic Cholecystectomies

Gaziosmanpasa Research and Education Hospital1 site in 1 country108 target enrollmentMay 1, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Postoperative Pain Management
Sponsor
Gaziosmanpasa Research and Education Hospital
Enrollment
108
Locations
1
Primary Endpoint
Total amount of opioid requirements
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

Comparison of Postoperative Analgesic Effects of M-TAPA and Anterior Quadratus Lumborum Blocks in Laparoscopic Cholecystectomies.

Detailed Description

In trunk blocks, the interfascial area between the anterior abdominal wall or back muscles is targeted. Local anesthetics are used for this purpose. Since there is no blood circulation and vascularization in the interfascial areas, the absorption of local anesthetics is slow, providing long-lasting analgesia. Therefore, they are used as a part of multimodal analgesia. The effectiveness of trunk blocks can vary depending on the patient's anatomical differences and previous surgeries, but on average, analgesic effectiveness lasts for 8-12 hours. Sometimes analgesic effectiveness extending up to 24 hours has been reported. In laparoscopic cholecystectomy operations, pain plays a role in postoperative atelectasis, pneumonia due to atelectasis, prolonged hospital stay, and discharge. To reduce the use of opioids due to their side effects such as nausea, vomiting, itching, constipation, and addiction, opioid-free analgesia is applied, and regional techniques are used. Quadratus lumborum blocks and M-TAPA blocks have been safely and easily applied in abdominal surgery in recent years thanks to developments in trunk blocks and ultrasound technology, and they are frequently preferred.

Registry
clinicaltrials.gov
Start Date
May 1, 2024
End Date
October 1, 2024
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

SERPİL ŞEHİRLİOĞLU

MD

Gaziosmanpasa Research and Education Hospital

Eligibility Criteria

Inclusion Criteria

  • scheduled for elective Laparoscopic chplecystectomy
  • Patients aged ≥18 years
  • American Society of Anesthesiologists physical status (ASA) Ⅰ-II

Exclusion Criteria

  • ASA III-IV patient
  • local anesthetic allergy
  • Infection at the procedure site Body Mass Index \>35 kg/m2 Anticoagulant use with bleeding disorder Chronic analgesia and opioid use with mental and psychiatric disorders Contraindications to regional anesthesia several lung and heart disease

Outcomes

Primary Outcomes

Total amount of opioid requirements

Time Frame: within 24 hours after the surgery

The total tramadol use of the patients in 24 hours will be recorded.

Secondary Outcomes

  • rescue analgesia(within 24 hours after the surgery)

Study Sites (1)

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