Structured Cognitive Therapy to Improve Neurocognitive Dysfunction in Older Intensive Care Unit Sepsis Survivors
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- Tailored Online Cognitive Rehabilitation
研究概览
简要总结
The purpose of this project is to test whether an online cognitive rehabilitation program or online thinking exercises helps improve memory and thinking in elderly patients who survive a severe infection.
详细描述
Currently, over 50% of patients are estimated to develop an Alzheimer's like disease following their hospitalization. This means they might have trouble remembering simple things or doing simple tasks. This can make returning to normal life difficult. This project will test whether online thinking exercises can help speed up patient's recovery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Admitted to the Intensive Care Unit (ICU) at Froedtert Memorial Lutheran Hospital (FMLH)
- •Diagnosis of Sepsis
- •Age 65 years or older
- •Required mechanical ventilation or vasopressor therapy while in the ICU
- •Had delirium while in the ICU
排除标准
- •Non-English Speaking
- •Severe Dementia that would interfere with the ability to participate in the study activities
- •Prior or current structural neurological injury that would confound study results
- •Inability to communicate for any reason
- •Current chemotherapy or radiation treatment
- •Recent history of substance abuse
- •Life expectancy < 6 months
- •Planned discharge to long term acute care facility or nursing home
- •Lack reliable access to the internet either through a computer or smart device
结局指标
主要结局
Tailored Online Cognitive Rehabilitation
时间窗: 3 months
Older survivors of sepsis will demonstrate \> 80% adherence to a tailored cognitive rehabilitation program
Adherence to Online Intervention Modules
时间窗: 3 months
In recruited survivors of sepsis investigator will measure adherence to a facilitated structured neurocognitive rehabilitation program (administered as one-hour sessions, three days per week for 3 months) via a computer or smart device/phone.
次要结局
- Improvement in Neurocognitive Function part 2(6 months)
- Improvement in Neurocognitive Function part 1(6 months)
- Measure Differences in Cognitive Performance(6 months)
研究者
Rahul Nanchal
Associate Professor of Medicine
Medical College of Wisconsin