NCT03483311Unknown不适用
Estimation of Tissue Level of Resolvin D1 in Psoriasis Before and After Narrowband UVB Phototherapy: a Case-control Study.
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Tissue levels of resolvin D1 in psoriatic patients before and after NB-UVB.
研究概览
简要总结
• Assessment of tissue level of resolvin D1 in psoriasis in comparison to its level in healthy controls in order to verify its role in the pathogenesis of psoriasis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with psoriasis (adults and children above 12years)
- •Both sexes.
- •New cases or cases not receiving any treatment for at least 3 months ago.
排除标准
- •Any contraindication to phototherapy treatment (e.g. Photosensitizing creams or medications, past skin cancer, especially melanoma, etc...)
- •Erythrodermic and pustular psoriasis.
- •History of autoimmune diseases or other systemic diseases (e.g. Alzheimer's disease, fibromyalgia, cystic fibrosis)
研究组 & 干预措施
psoriasis patients
Experimental
Tissue levels of resolvin D1 in psoriatic patients before and after NB-UVB.
干预措施: skin biopsy before and after NB-UVB phototherapy (Other)
controls
Experimental
Tissue levels of resolvin D1 in controls
干预措施: skin biopsy before and after NB-UVB phototherapy (Other)
结局指标
主要结局
Tissue levels of resolvin D1 in psoriatic patients before and after NB-UVB.
时间窗: 6 months
次要结局
未报告次要终点
研究者
Maha Fathy Elmasry
principal investigator
Cairo University
研究点 (2)
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