comparing two drugs in head injury patients undergoing surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/08/035323
- Lead Sponsor
- Intramural grant from institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients 18 â?? 60 years ofage
ASA1-3
Emergency SDH evacuation
GCS <13
Exclusion Criteria
1.Allergy to medications
2.Pregnant and nursing women
3.Type 2 heart block
4.Heart rate <50 beats per minute
Hemodynamically unstable patients (Systolic blood pressure less than 90mmHg)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the mean propofol consumption between dexmedetomidine and fentanyl based TIVA in patients with acute traumatic subdural hematoma undergoing craniotomy for evacuation of subdural hematomaTimepoint: Mean propofol consumption at 60th min, 120th min, 180th min, 240th min, 300th min, 360th minute after the starting of surgery.
- Secondary Outcome Measures
Name Time Method Comparison of serum S100β levels between the groups at two time points (pre induction and end of surgery)Timepoint: sample will be collected before induction and one more sample will be collected at the end of the surgery and will be analysed