Comparison of the effect of adding dexmedetomidine or fentanyl to ropivacaine on sensory and motor characteristics and analgesia after orthopedic lower limb surgery
Phase 3
- Conditions
- Sensory and motor nerve blocks.
- Registration Number
- IRCT20130311012782N41
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Weight less than 100 kg
Patient undergoing lower extremity orthopedic surgery
Exclusion Criteria
Pregnancy
History of addiction or smoking, drugs and alcohol
liver disease
cardiovascular disease
Chronic pain report lasting more than 6 months
Drug sensitivity or ropivacaine, fentanyl and dexmedetomidine
contraindication of spinal anesthesia
Long-term drug history or opioid and NSAIDs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to start sensory block. Timepoint: After the intrathecal injection of the anesthetic drug. Method of measurement: Sensory testing with no sensation of tingling with Nidel No. 23 is evaluated as subcutaneous stimulation.
- Secondary Outcome Measures
Name Time Method Postoperative pain. Timepoint: Every 15 minutes in recovery and every 2 hour in ward. Method of measurement: With using visual Analog Scale. The criterion is a line between zero to ten and zero in the sense of no pain and ten being the most severe equivalent of the pain experienced by the patient. With this concept, the patient is asked to indicate their current pain intensity on line.;Blood pressure. Timepoint: Every 15 minutes during surgery and recovery. Method of measurement: Pulse Oximeter.;Heart rate. Timepoint: Every 15 minutes during surgery and recovery. Method of measurement: Pulse Oximeter.