management of white patches through ayurvedic medicines Mitrapanchak yoga and Avalgujbeejadi lepa

Phase 1

Completed

• Conditions: Vitiligo

• Registration Number: CTRI/2016/08/007171
• Lead Sponsor: INSTITUTE FOR POST GRADUATE TRAINING AND RESEARCH IN AYURVEDA

Brief Summary

***Shwitra*** is a disease described in Ayurveda; which is produced byvitiation of *Vata, Pitta* and *Kapha Doshas*. The signs and symptoms of *Shwitra* are; non exudative white, red orcoppery-red coloured patches on the skin, destruction of the skin lusture, lossand discolouration of the hair, roughness, dryness, itching and burningsensation of the patches. It can be correlated with Vitiligo which isprogressive whitening of the skin and hair characterized by the total absenceof melanocytes in affected areas of the skin. **Aim:**To assess and compare the clinical efficacy of *Mitrapanchaka Yoga* withand without *Avalgujbeejadi lepa* inthe management of *Shwitra* (Vitiligo).**Material and methods:**  In this trial, 34 patients were registered, out of which 30completed the treatment. Patients were randomly divided in twogroups with the help of computer generated random selection method viz. Group Aand Group B. In Group A classical *Mridu Samshodhana* was given followed by oral administration of *Mitrapanchaka Yoga* as a *Shamana Yoga*, followed by *Avalgujbeejadilepa* for local application*.* InGroup B patients were treated with *MriduSamshodhana* followed by oral administration of *Mitrapanchaka Yoga*internally*.*   Special scoring pattern was adopted forscrutinizing the symptomatology. The score was given on the basis of Size,Colour, Number of patches, percentage of body area involvement and chronicityof patches. VASI Score toknow overall effect of therapy on two groups and VIS-22 Score for each patientwas calculated **Results:**On Applying VASI Score both groups showedhighly significant results.VIS-22 Score was suggestive of high psychologicalinvolvement in disease. **Conclusion:**Oncomparison group A showed better results in percentage changes, resultdifference was significant in improvement in number of patches in Group A, which suggeststhat *Mitrapanchaka* *Yoga* and *Avalgujabeejadi* *Lepa* together givebetter results than *Mitrapanchaka* *Yoga* alone.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-01
• Last Update Posted: 2017-04-21

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Patients having signs and symptoms of Shwitra (vitiligo).
• Patients between age group of 16 years to 60 years will be selected.

Exclusion Criteria

• 1.Patients having chronic condition, more than 10 years 2.Patients having all other de-pigmentory disorders.
• 3.Patients having serious cardiac, renal, hepatic diseases.
• 4.Patients having major illness like IDDM, NIDDM which are poorly controlled and any other systemic diseases.
• 5.Patches due to burning, chemical explosion etc.
• 6.Located at region of Guhya (Genital region), Panitala (Foot soals and Hand soals), Oshtha (Lips), Aekanga, Sarvanga(whole body).
• 7.Patches with Raktaloma, Sansakta Mandala.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
will be evaluated	will be evaluated after 60 days

Secondary Outcome Measures

Name	Time	Method
will be evaluated	will be evaluated after 60 days

Trial Locations

Locations (1)

ipgtra jamnagar; 🇮🇳 Jamnagar, GUJARAT, India

ipgtra jamnagar

🇮🇳Jamnagar, GUJARAT, India

Nirank Kumar

Principal investigator

9924304547

nirank1989@gmail.com