NL-OMON39735
Completed
N/A
Respiratory, hemodynamic and inflammatory effects of induced HypothermiA using NoVAtherm with extra corporeal membrane ventilator iLA-Activve in patients with acute respiratory distress syndrome (ARDS) - HAVAnA study
ICU volwassen / L.E.I.C.A.0 sites30 target enrollmentTBD
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- ARDS
- Sponsor
- ICU volwassen / L.E.I.C.A.
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Suffering of a clinical condition associated with ARDS
- •2\) ARDS according to the Berlin definition (P/F \< 200 with PEEP \> 5 cmH2O; bilateral pulmonary opacities at chest X\-ray; respiratory failure not fully explained by cardiac failure or volume overload)
- •3\) Mechanical ventilation with maximum inspiratory pressure levels (Pmax) of \> 30 cm H2O, while maintaining tidal volume ventilation of 6\-8 ml/kg ideal body weight and permissive hypercapnia with an arterial pH \< 7\.25\.
Exclusion Criteria
- •1\) Contra\-indication for (low dose of) heparin
- •2\) Severe shock, requiring norepinephrin dose of \> 2 mg/hour
- •3\) Severe hypoxia, requiring referral for extra corporeal membrane oxygenation
Outcomes
Primary Outcomes
Not specified
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