NL-OMON44494已完成不适用
The acute metabolic and cardio respiratory effects of neuromuscular electrical stimulation in critically ill, mechanically ventilated patients: a pilot study. - Neuromuscular electrical stimulation in critically ill patients (NMES-ICU)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- older than 18 years
- •- sedated (all levels of sedation) or not yet responsive (Ramsay 5-6)
- •- Volume supported or pressure supported mechanically ventilated
- •- respiratory and hemodynamically stable
- •- signed formed consent by legal representative
排除标准
- •- known systemic neuromuscular disease (eg, Guillain-Barre syndrome)
- •- ability to actively move the legs
- •- life expectancy less than 24 hours determined by the physician
- •- in contact isolation
- •- pacemaker or implanted cardiac defibrillator
- •- pregnancy
- •- body mass index of > 35kg/m2
- •- condition in the lower extremity preventing treatment (Skin lesions, fractures, amputations, known or suspected malignancy in the legs, myopathy, paresis of the stimulated muscles, epilepsy, allergic reactions to the electrodes, peripheral edemas counteracting NMES, heavy ischaemia of the lower extremities
- •- corticosteroids usage (>7.5mg/day >3 months)
- •- positive end-expiratory pressure (PEEP) > 14 cmH2O, Fraction of inspired oxygen (FiO2) >0.6 and the presence of air leakage (Haugen, Chan, & Li, 2007) (Kho et al., 2012, Gruther et al., 2010).
- •- patients that receive therapeutic hypothermia
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