NL-OMON44494
Completed
N/A
The acute metabolic and cardio respiratory effects of neuromuscular electrical stimulation in critically ill, mechanically ventilated patients: a pilot study. - Neuromuscular electrical stimulation in critically ill patients (NMES-ICU)
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- ICU acquired weakness
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 11
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- older than 18 years
- •\- sedated (all levels of sedation) or not yet responsive (Ramsay 5\-6\)
- •\- Volume supported or pressure supported mechanically ventilated
- •\- respiratory and hemodynamically stable
- •\- signed formed consent by legal representative
Exclusion Criteria
- •\- known systemic neuromuscular disease (eg, Guillain\-Barre syndrome)
- •\- ability to actively move the legs
- •\- life expectancy less than 24 hours determined by the physician
- •\- in contact isolation
- •\- pacemaker or implanted cardiac defibrillator
- •\- pregnancy
- •\- body mass index of \> 35kg/m2
- •\- condition in the lower extremity preventing treatment (Skin lesions, fractures, amputations, known or suspected malignancy in the legs, myopathy, paresis of the stimulated muscles, epilepsy, allergic reactions to the electrodes, peripheral edemas counteracting NMES, heavy ischaemia of the lower extremities
- •\- corticosteroids usage (\>7\.5mg/day \>3 months)
- •\- positive end\-expiratory pressure (PEEP) \> 14 cmH2O, Fraction of inspired oxygen (FiO2\) \>0\.6 and the presence of air leakage (Haugen, Chan, \& Li, 2007\) (Kho et al., 2012, Gruther et al., 2010\).
Outcomes
Primary Outcomes
Not specified
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