the Prevalence of "Wearing-off" in Patients With Parkinson's Disease in Shanghai, China: a Cross-sectional Investigation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,480
- 试验地点
- 1
- 主要终点
- the prevalence of wearing off effect in Parkinson's patients that received stable anti Parkinsonian therapy in Shanghai of China
研究概览
简要总结
The study would be designed as a multi-center cross-sectional investigation on the prevalence of Wearing-off in Parkinson's patients in Shanghai as well as related influencing factors.
详细描述
PD patients would be randomly recruited into this investigation from around thirty hospital covering the 16 districts of Shanghai. The wearing off would be defined by two methods: the doctors' judgement or the WOQ-9 questionnaire which was a patient-determining tool. The investigation also includes the medicine, the severity of PD symptoms, the demographic factors. The study would be designed with the purpose of clarifying the prevalence of the "wearing-off" and its related influencing factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 35 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •have been clinical diagnosed with Parkinson's disease
- •have received stable anti-Parkinson's treatment before being recruited to the study.
排除标准
- •being suspicious of atypical Parkinson syndrome or secondary Parkinson syndromes
- •have not received anti Parkinsonian treatment.
- •being combined with serious cognitive dysfunction or psychiatric symptoms
- •unable to complete the investigations.
结局指标
主要结局
the prevalence of wearing off effect in Parkinson's patients that received stable anti Parkinsonian therapy in Shanghai of China
时间窗: 1 year
every participant receives a clinical assessment of the wearing-off symptoms by a physician and completes a self rating scale of the wearing-off 9 questionnaire (WOQ-9) to obtain a prevalence of wearing-off positive individuals( wearing-off would be diagnosed by physicians during the clinical assessments)
次要结局
- the sensitivity and the specificity of the wearing-off 9 questionnaire in the diagnosis of wearing-off effect in Parkinson's disease.(1 year)
- the risk factors of wearing-off in Parkinson disease(1 year)