LARS in Ovarian Cancer Patients
- Conditions
- Low Anterior Resection Syndrome
- Interventions
- Other: low anterior resection syndrome evaluation
- Registration Number
- NCT04279080
- Lead Sponsor
- Medical University of Vienna
- Brief Summary
Background:
Low anterior resection syndrome (LARS) is a common functional disorder after low anterior resection impacting quality of life. Data on LARS derives nearly exclusively from rectal cancer studies. Therefore, the study was designed to assess LARS in advanced epithelial ovarian cancer (EOC) patients, who underwent rectal resection and to compare it with a female rectal cancer cohort.
Methods:
A cross-sectional multi-centre analysis was performed for female patients suffering from either rectal or EOC who received a low anterior resection as part of their therapy regimen. None of the patients received pre- or postoperative radiotherapy. LARS was defined by using the validated LARS score and its severity was divided into "no", "minor" and "major LARS".
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 125
- low anterior resection because of ovarian or rectal cancer
- neoadjuvant or adjuvant radiotherapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 1 low anterior resection syndrome evaluation rectal cancer patients 2 low anterior resection syndrome evaluation ovarian cancer patients
- Primary Outcome Measures
Name Time Method functional bowel outcome after low anterior resection 1 year low anterior resection syndrome score, questionnaire via telephone call or personal contact
- Secondary Outcome Measures
Name Time Method