Diversity of intestinal microbiota among Thai IBS-D patients and impact of probiotic as an adjuvant therapy
Phase 3
Completed
- Conditions
- Gut microbiota Irritable bowel syndrome with diarrheagut microbiotairritable bowel syndrome with diarrhea
- Registration Number
- TCTR20191211006
- Lead Sponsor
- Academic promotion and development unit, Faculty of Medicine, Prince of Songkla University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Diagnosed IBS-D according to ROME IV criteria
Exclusion Criteria
Received probiotic or antibiotic within 3 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of gut microbiota at baseline 16s rRNA sequencing gene
- Secondary Outcome Measures
Name Time Method IBS severity at baseline, 4 wks and 8 wks after probiotic IBS-SSS scores ,Quality of life at baseline, 4 wks and 8 wks after probiotic SF-36 scores ,Amount of gut microbiota 8 wks after probiotic 16s rRNA sequencing gene