The BioGene Bank Cohort Study is a Collection of Human Blood Samples (DNA and Plasma) Along With De-identified (Coded) Health Information, Questionnaire Responses on Environment and History of Family Disease to be Used for Research
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Northwell Health
- Enrollment
- 7,056
- Locations
- 1
- Primary Endpoint
- Time from symptoms to diagnosis of autoimmune diseases
Study Overview
Brief Summary
The BioGene bank: Is a centralized collection of human blood samples along with de-identified (coded) health information, environmental factors, family disease histories and information from DNA. Limited to the NSLIJHS catchment area.
Detailed Description
The purpose of the BioGene Bank Cohort is to collect blood and store DNA from blood, along with health information to study how genetic variation in the population is associated with particular diseases, treatments and medical outcomes. Investigators may study the entire range of diseases and medical problems that exist within the NSLIJHS, including medical, surgical, psychiatric, pediatric and obstetric conditions. The specimens and medical information will be kept at a central Biorepository. This research study does not involve any treatment and individual research results are not provided.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 1 Year to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Anyone receiving care at the NS LIJ Health System would be eligible to join the BioGene Bank Cohort.
- •Participants' family members who may or may not have medical records at NSLIJHS.
Exclusion Criteria
- •Patients unable to give consent because they are decisionally impaired or have a language barrier that cannot be overcome.
- •Patients unable to provide a blood sample because it would adversely affect their health or who refuse to provide blood sample or share future discarded biological samples.
- •Patients <10kg in weight
Outcomes
Primary Outcomes
Time from symptoms to diagnosis of autoimmune diseases
Time Frame: 10 years
Documentation of symptoms to diagnosis of autoimmune disease(s)
Secondary Outcomes
- Chart Review of Participants who are diagnosed with autoimmune disease(average of 10 years)
Investigators
Peter Gregersen
Center Head: Robert S. Boas Center for Genomics and Human Genetics
Northwell Health