Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atrial Fibrillation
- Sponsor
- The Cleveland Clinic
- Enrollment
- 1300
- Locations
- 1
- Primary Endpoint
- Genetic variants associated with atrial fibrillation
- Status
- Active, not recruiting
- Last Updated
- 7 months ago
Overview
Brief Summary
The purpose of this study is to establish a genebank repository of blood samples and data to generate information about the hereditary (genetic) basis of atrial fibrillation.
Detailed Description
Blood samples and data will be collected from subjects with atrial fibrillation and normal controls. The primary aim of future research using these samples is to identify mechanisms and pathogenesis of atrial fibrillation. Through this information, we hope to identify targets for new therapies and improve knowledge and understanding of atrial fibrillation. Identification of disease genes could improve strategies that prevent progression of atrial fibrillation to more persistent disease.
Investigators
Mina Chung, MD
Principal Investigator
The Cleveland Clinic
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Genetic variants associated with atrial fibrillation
Time Frame: Baseline
Genome-wide association study of atrial fibrillation