Distribution of Helicobacter Pylori After Gastrectomy

• Conditions: Helicobacter Pylori Infections
• Interventions: Diagnostic Test: Endoscopic biopsy

• Registration Number: NCT03419936
• Lead Sponsor: Asan Medical Center

Brief Summary

The purpose of this study is to know the distribution of Helicobacter pylori in stomach before subtotal gastrectomy and after subtotal gastrectomy.

Detailed Description

Endoscopy and biopsy will be performed to investigate the distribution of Helicobacter pylori before and after subtotal gastrectomy.

Study Timeline

• Study Start: 2016-03-21
• Status Verified: 2018-01
• Study First Submitted: 2018-01-27
• Study First Submitted QC: 2018-01-27
• Last Update Submitted: 2018-01-27
• Study First Posted: 2018-02-05
• Last Update Posted: 2018-02-05
• Primary Completion: 2020-03-21
• Study Completion: 2020-03-21

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Patients who are indicated to subtotal gastrectomy due to gastric neoplasm
2. Aged between 19 to 75 years
3. Informed consent

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Exclusion Criteria

1. Previous history of Helicobacter pylori eradication
2. Previous history of proton pump inhibitor use within 6 months

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Helicobacter pylori(HP) positive	Endoscopic biopsy	Participants who are diagnosed with gastric cancer and Helicobacter Pylori infection will be treated with subtotal gastrectomy.

Primary Outcome Measures

Name	Time	Method
Distribution of Helicobacter Pylori After Gastrectomy	Change in the distribution of Helicobacter Pylori at 2 years	Analysis the change of Helicobacter pylori according to the subtotal gastrectomy

Secondary Outcome Measures

Name	Time	Method
Change of atrophy after gastrectomy	Change in the atrophic status at 2 years	Analysis the change of atrophic status according to the subtotal gastrectomy

Trial Locations

Locations (1)

Asan Medical Center; 🇰🇷 Seoul, Songpa-gu, Korea, Republic of