Helicobacter Pylori and Proton Pump Inhibitor

Completed

• Conditions: Helicobacter Infections
• Interventions: Drug: PPI (proton pump inhibitor)

• Registration Number: NCT02449941
• Lead Sponsor: Asan Medical Center

Brief Summary

The purpose of this study is to know the distribution of HP in stomach before use of PPI, during use of PPI, and after stop of PPI.

Detailed Description

Endoscopy and biopsy will be performed to investigate the distrubition of HP before, during, and after using PPI.

Study Timeline

• Study Start: 2014-03
• Study First Submitted: 2015-05-14
• Study First Submitted QC: 2015-05-18
• Study First Posted: 2015-05-21
• Status Verified: 2016-12
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Last Update Submitted: 2016-12-04
• Last Update Posted: 2016-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Patients who are indicated to endoscopic resection due to gastric neoplasm
2. Aged between 19 to 65 years
3. Informed consent

Exclusion Criteria

1. Previous history of HP eradication
2. Previous history of PPI use within 6 months
3. No HP infection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Helicobacter pylori(HP) positive	PPI (proton pump inhibitor)	Participants who are diagnosed with Helicobacter Pylori infection through ESD(endoscopic submucosal dissection) will be treated with PPI (proton pump inhibitor).

Primary Outcome Measures

Name	Time	Method
Analysis the change of Helicobacter pylori distribution according to the use of proton pump inhibitor	Change in the distribution of Helicobacter Pylori(HP) at 4 months.

Secondary Outcome Measures

Name	Time	Method
Analysis the change of HP distribution according to the use of PPI in atrophic change of stomach	Change in the distribution of Helicobacter Pylori(HP) at 4 months.

Trial Locations

Locations (1)

Asan Medical Center; 🇰🇷 Seoul, Songpa-gu, Korea, Republic of