Comparative effect of a mouthwash formulated with Spirulina platensis and Chlorhexidine on chronic pariodontitis in patients with cardiovascular disease: a Clinical trials pilot study

Not Applicable

• Conditions: Oral Health

• Registration Number: PACTR202206703009274
• Lead Sponsor: PIEME CONSTANT ANATOLE

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-07
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Adult patients (18 years and older),
- men or women with: (1) cardiovascular disease; (2) superficial chronic periodontal inflammation: = 2 inter proximal sites with a loss of attachment = 3mm or =2 inter proximal sites with a pocket depth = 4mm (not on the same tooth) or a single site with a depth of pocket = 5mm (CDC-AAP definition of periodontitis); (3) at least 10 teeth in the oral cavity; (4) -All patients gave written informed consent.

Exclusion Criteria

- Patients lost to follow-up for 7 days; those who have withdrawn their informed consent;
-Patients with cardiovascular diseases (CVD) but with moderate / severe chronic periodontitis; patients with CVD at risk of endocarditis: valve disease, valve prosthesis, interventricular communication, persistent aortic duct; patients taking antibiotics, anti-inflammatories, tobacco; or having an allergy to algae; patients using toothpaste or any other medicament with periodontal action including toothpaste based on sodium bicarbonate; and pregnant women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified