Glucose response to single sessions of resistance and aerobic exercise in people with type 2 diabetes

Not Applicable

• Conditions: Type 2 Diabetes; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12610000906055
• Lead Sponsor: Dr Amanda Benson

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-10-25
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

Males and females aged 50-70 years with established type 2 diabetes (>6 months)
Treated with exogenous insulin
Stable weight over the past 3 months
Stable glycaemic control of greater than or equal to 8 weeks
HbA1c between 7.0% and 10% at screening

Exclusion Criteria

Use of beta-blockers and/or oral anti-hyperglycaemic medication for less than 6-months
Impaired liver function
Renal failure
Severe retinopathy
Recent myocardial infarction
Unstable angina
Chronic heart failure
Recent exacerbation of respiratory disease
Exceeding the national recommendations for exercise, which are: at least 30 minutes of moderate-intensity aerobic activity on 5 days of the week for at least 3 months (150 minutes plus per week) and/or at least 30 minutes of vigorous-intensity aerobic activity on 3 days of the week for at least 3 months (90 minutes plus per week)
Any strength training for 2 or more sessions per week in last 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glucose variation using a continuous glucose monitor[continuous for 3 days post intervention]

Secondary Outcome Measures

Name	Time	Method
Insulin sensitivity using HOMA calculations from fasting glucose and insulin levels. Adiponectin will also be measured as a surrogate marker.[immediately post exercise & 72 hours post exercise];Aspirin resistance will be measured by separating some of the collected blood into two separate tubes, one containing a vehicle agent and one conataining aspirin before being analysed for platelet aggregation.[immediately post exercise & 72 hours post exercise]