MedPath

Factors Contribute to Very Late Stent Thrombosis After New Generation DES Implantation in China

Completed
Conditions
Stent Thrombosis
Registration Number
NCT03491891
Lead Sponsor
The First Hospital of Jilin University
Brief Summary

The investigators sought to identify and verify the potential correlates and mechanisms of Very Late Stent Thrombosis (VLST) after the implantation of new generation drug eluting steng in China from an analysis of multicenter registries.

Detailed Description

This study represents a patient-level pooled analysis of patients undergoing percutaneous coronary intervention with stent implantation for acute coronary syndrome. Multiple aspects including clinical, angiographic, procedural characteristics , intravascular imaging results and blood samples were collected at index PCI and the time of VLST or CAG during follow-up, in order to reveal the potential mechanisms or risk factors that contribute to the development of VLST.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
8476
Inclusion Criteria
  • Patients>18y,admitted for acute coronary syndrome,successfully underwent PCI with at least one stent, sign informed consent.
Exclusion Criteria
  • Expected lifetime was less than 1 year for any severe disease(such as tumor,severe respiratory failure et al). There is a surgical plan for important organs within 1 year after surgery and anti-platelet drugs should be discontinued. Refusing to sign informed consent.Died prior to discharge. Poor compliance, unable to participate in regular follow-up.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Very Late Stent ThrombosisFive years

very late stent thrombosis demonstrated by coronary angiography

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Jilin University 1st Hospital

🇨🇳

Changchun, Jilin, China

© Copyright 2025. All Rights Reserved by MedPath