NL-OMON38270CompletedPhase 2
Effects of Sildenafil on pulmonary artery pressure in patients with heart failure with preserved ejection fraction and pulmonary hypertension - Sildenafil in HFpEF and PH
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Enrollment
- 52
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •PH secondary to HFpEF defined as mean PAP larger 25 mmHg, wedge larger 15, LVEF larger 45
- •NYHA II-IV
Exclusion Criteria
- •other cause of PH
- •severe noncardiac limitation to exercise
- •coronary ischemia or recent myocardial infarction (<6 months)
- •hypotension , RR< 90/50
- •ongoing nitrate therapy
- •significant left sided valve disease
- •severe liver dysfunction
- •unable to read and comprehend Dutch language
Investigators
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