CTRI/2009/091/000017已完成2 期
Role of sildenafil in secondary pulmonary artery hypertension due to chronic obstructive pulmonary disease
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- self
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Ambulatory patients having severe or very severe COPD according to GOLD (global initiative for chronic obstructive lung disease) classification were recruited in the study if they had: past history of smoking at least 20 pack years. They had pulmonary artery systolic pressure of more than 40 mmHg as measured by Doppler echocardiography
排除标准
- •Patients were not included if they had: acute exacerbation of COPD in last month, history of bronchial asthma or more than 12% increase in FEV1(forced expiratory volume one second) with bronchodilator, history of primary cardiac disease or documented ischaemic heart disease, use of nitrates or other vasodilator throughout the study period, hemoglobin less than 12g/dl, any severe concomitant disease, evidence of pulmonary artery hypertension due to any other cause such as pulmonary thromboembolism, Human Immunodeficiency Virus, scleroderma, congenital heart disease etc. and de-compensated right or left heart failure.
研究者
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