临床试验/CTRI/2019/09/021287

CTRI/2019/09/021287招募中4 期

Standard versus low-dose cyclical Cyclophosphamide and Steroids in the treatment of Primary Membranous Nephropathy- a randomised controlled trial

Postgraduate Institute of Medical Education and Research0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年8月19日

试验速览

阶段: 4 期
状态: 招募中
发起方: Postgraduate Institute of Medical Education and Research

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Interventional

入排标准

入选标准

•1. Biopsy-proven primary membranous nephropathy
•2. Nephrotic syndrome despite non-immunosuppressive anti-proteinuric therapy for 3 months or membranous nephropathy with deep vein thrombosis (DVT) or requiring hospitalization for complications of nephrotic syndrome
•3. Patients showing severe or disabling symptoms related to nephrotic syndrome, or severe hypoalbuminemia ( <2 g/dL) that can be included before the completion of 3-month observation period at the discretion of the investigator independent of the proteinuria value.

排除标准

•1)Patients with eGFR >45 ml/min/1.73m2
•2)Prior, active infection including hepatitis B/C and HIV infection,
•3)Positive for anti-nuclear factor,
•4) Monoclonal proteins in serum/urine,
•5)Any suggestion of malignancy on ultrasonography,
•6)Hypocomplementaemia,
•7)Presence of tubular atrophy and
•8)Pre-existing DM,
•9)Abnormal liver function tests and secondary MN
•10)Any immunosuppressive therapy in the last 12 months

研究者

发起方

Postgraduate Institute of Medical Education and Research

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