To study the effect of bhunimbadi churna vati in alcoholic hepatitis
Phase 3
- Conditions
- Health Condition 1: K701- Alcoholic hepatitis
- Registration Number
- CTRI/2023/08/056282
- Lead Sponsor
- Dr Amatullah Ataullah Dalvi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Able to provide written consent.
2. Male or female patients between 22- 55 yrs of age.
3. AST Value 50u/l to 400u/l
4. Total bilirubin in the range of 2 mg/dl to 15mg/dl.
5. AST:ALT > 1.5
Exclusion Criteria
1.Other liver pathology like viral hepatitis, drug induced hepatitis, non-alcoholic hepatitis,
immunocompromised patients.
2.Patient with alcoholic withdrawal symptoms such as hallucination, abusive, agitated &
aggressive behavior.
3. K/C/O - liver cirrhosis, liver cancer & ascites.
4.K/C/O - renal disorder, cardiac disorder, hypertension and other chronic disorder, endocrinological
disorder.
5.K/C/O - Hemochromatosis, Wilson disease and other autoimmune disorder.
6.Pregnant & lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method SUBJECTIVE CRITERIA- <br/ ><br>1.Twacha-peetavarna (Yellowish discoloration of skin) <br/ ><br>2.Nakha-peetavarna (Yellowish discoloration of nails) <br/ ><br>3.Peeta-netrata(Yellowish discoloration of eyes) <br/ ><br>4.Peeta mutra varna <br/ ><br>(Yellowish discoloration of urine) <br/ ><br>5.Peet-shakrit(Yellowish discoloration of stool) <br/ ><br>6.Mukha- peetata <br/ ><br>(Yellowish discoloration of face) <br/ ><br>7.Jwar (Fever) <br/ ><br>8.Shudhamandya <br/ ><br>(Loss of appetite) <br/ ><br>9.Daurbalya <br/ ><br>(Weakness) <br/ ><br>10.Aruchi <br/ ><br>(Loss of taste) <br/ ><br>11.Hrullas (Nausea) <br/ ><br>OBJECTIVE CRITERIA- <br/ ><br>CBC,LFTTimepoint: Baseline and After 4 weeks
- Secondary Outcome Measures
Name Time Method A.Changes in Subjective parameters like <br/ ><br>1.Twacha peetavarna <br/ ><br>2.Nakha peetavarna <br/ ><br>3.Peeta netrata <br/ ><br>4.Peeta mutra varna <br/ ><br>5.Peeta shakrit <br/ ><br>6.mukha peetata <br/ ><br>7.Jwar <br/ ><br>8.Shudhamandya <br/ ><br>9.Daurbalya <br/ ><br>10.Aruchi <br/ ><br>11.Hrullas. <br/ ><br>B.Changes in objective parameters like CBC & LFT which includes <br/ ><br>1.serum bilirubin <br/ ><br>2.AST-ALT ratio.Timepoint: Baseline & after 4 weeks