Compare the effects of two drugs namely Magnesium and Rocuronium during intubation in general anesthesia
Phase 4
- Conditions
- Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services
- Registration Number
- CTRI/2020/02/023399
- Lead Sponsor
- SRM Medical College and Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status 1 & 2
BMI 18.5 - 24.9 kgm2
Mallampatti grade 1 & 2
Elective surgery under general anesthesia
Exclusion Criteria
patients with neuromuscular disease
renal or hepatic insufficeincy
allery to study drugs
drugs that influence neuromuscular function
breast feeding mothers or pregnancy
anticipated difficult airway
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Intubation conditions- which are assessed as excellent, good and poor using variables such as relaxation of jaw, resistance to blade insertion, position of vocal cords, and reaction to intubation <br/ ><br>2. Duration of intubation is assessed as return of neromuscular blockade as TOF of twoTimepoint: Baseline single twitch, TOF at 170seconds after priming dose of Rocuronium, TOF at the end of the procedure before giving reversal agent
- Secondary Outcome Measures
Name Time Method To compare the dosage of Rocuronium required in magnesium pretreatmentTimepoint: 1. Total dose of Rocuronium used in mgs <br/ ><br>2. Duration of muscle relaxation attained <br/ ><br>3. Dosage of sedatives and analgesics required in the postoperative period