To compare the effect of fall in blood pressure by nitroglycerin and labetalol in patients undergoing functional endoscopic sinus surgery.
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/12/060596
- Lead Sponsor
- Department of Anaesthesiology,Sawai Man Singh Medical College And Attached Hospitals, Jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients undergoing elective functional endoscopic sinus surgery
2. Patients of either sex willing to give consent
3. Age group of 18 to 45 years.
4. ASA grade I & II
Exclusion Criteria
1. History of allergy to any of the study medication
2. Patient with pre-existing bleeding and coagulation abnormalities
3. Patients with diabetes, hypertension, cardiovascular disease
4. Cerebrovascular disorders
5. Renal and hepatic impairment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To determine and compare the serum lactate levels at different time intervals between the groups. <br/ ><br>2. To determine and compare peripheral perfusion index between the two groups.Timepoint: 120 minutes
- Secondary Outcome Measures
Name Time Method 1. To determine and compare the systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and heart rate (HR) at different time intervals between the groups. <br/ ><br>2. To compare the quality of intra-operative surgical field score by using a categorical scale in both the groups (0-5). <br/ ><br>3. To compare the intra operative blood loss between the two groups.Timepoint: 120 minutes