Italian National Study on the Critically Ill Liver Transplant Patient With an Infection
- Conditions
- InfectionSepsisLiver TransplantationIntensive Care Unit
- Registration Number
- NCT03363646
- Lead Sponsor
- Azienda Ospedaliero, Universitaria Pisana
- Brief Summary
Despite major advances, infections remain one of the major causes of morbidity and mortality in patients undergoing orthotopic liver transplantation (OLT). Furthermore, data on the epidemiology, severity, and type of post-OLT infections nowadays available come from dated, monocentric, retrospective series. Finally, there is no available data focused on the critical OLT patient admitted to the Intensive Care Unit (ICU). Therefore this study was conceived (1) to describe incidence, severity, epidemiology and outcomes of infections recorded in OLT patients in the ICU (first or re-admission ); (2) to identify possible risk factors and (3) to report the type of the involved microorganism with their antibiotic sensitivity pattern
- Detailed Description
The study will record clinical, epidemiological and microbiological data from the clinical files of OLT patients admitted at italian ICUs
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical 18 months number and severity of infectious episodes
microbiological 18 months describe the type of infectious agents
- Secondary Outcome Measures
Name Time Method Resistance 18 months antibiotic resistance patters of the isolates
Trial Locations
- Locations (1)
U.O. Anestesia e Rianimazione Trapianti
🇮🇹Pisa, Italy