A COMPARATIVE STUDY OF INTRATHECAL HYPERBARIC BUPIVACAINE WITH FENTANYL AND INTRATHECAL HYPERBARIC ROPIVACAINE WITH FENTANYL IN ELECTIVE LOWER SEGMENT CAESAREAN SECTION.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the onset of analgesia between the two different study groups concerning the nature of sensory block, motor block, and duration of analgesia.
研究概览
简要总结
Spinal anaesthesia is the standard Anesthetic choice for lower segment cesarean section (LSCS), except in a few cases where it is contraindicated. This study is to compare the effects of the combination of either Ropivacaine, or Bupivacaine with fentanyl (one of the most used adjuvants in intrathecal administration). they have additive effects when applied together in the subarachnoid space, with greater analgesic quality and duration, safety, and also longer-lasting post-surgical analgesia, which is clinically significant. The rationale behind this study is to observe and assess the effect of 0.5%hyperbaric bupivacaine with fentanyl and 0.75% hyperbaric ropivacaine with fentanyl when administered through intrathecal route for elective caesarean deliveries
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •Those who consented to be part of the study and gave written consent women who are undergoing elective cesarean section for baby delivery ASA II patients.
排除标准
- •ASA Grade III or Above Patients in whom spinal anesthesia was contraindicated Pre-operative hemodynamic instability, maternal heart disease, and severe anaemia History of allergy to local anaesthetic or opioids.
结局指标
主要结局
To compare the onset of analgesia between the two different study groups concerning the nature of sensory block, motor block, and duration of analgesia.
时间窗: After the Administration of intrathecal local anaesthetics and opioids postoperatively, the patient is observed every 15mins 30 minutes 1 hr then every 1hr up to 24hrs
次要结局
- To find out the effectiveness and hemodynamics of the drugs.(To find out the Pain score at 30 min,4hr, 8hr, 12hr post-op.)
研究者
Rajarajeswari M
Sree Balaji Medical College and Hospital