A Study to determine the efficiency of a specific modality of ultrasound (tissue doppler imaging) in imaging an abddominal muscle (diaphragm) to predict if patients can be successfully liberated from ventilator
- Conditions
- Health Condition 1: J989- Respiratory disorder, unspecified
- Registration Number
- CTRI/2020/12/029533
- Lead Sponsor
- Gautham Chandran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
On mechanical ventilation >48hrs.
Readiness for weaning from mechanical ventilation
Recovery from the cause of respiratory failure
Stable hemodynamic parameters.
Low or no vasopressor requirement
No sedative agents or NMBA > 24 h before enrolment.
Patients who meet criteria for spontaneous breathing trial
Fio2 < 40
Pressure Support (PS) < 10
Positive End Expiratory Pressure (PEEP) <
Respiratory Rate <30
P/F ratio >200
Glasgow coma scale - GCS >14 ,
RASS: -2 to +2.
Pregnant Women
Presence of Pneumothorax or Ascites
H/o either neuromuscular disease, thoracic surgery, Diaphragmatic Palsy, Cervical Spine Injury
Weaning failure definitely caused by upper airway obstruction
Planned prophylactic NIV after extubation.
Poor ultrasound windows and image
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the diagnostic accuracy of diaphragmatic pulse-wave tissue doppler imaging (PW-TDI) parameters in predicting weaning outcomes in critically ill mechanically ventilated patientsTimepoint: Ultrasound measurements will be taken at the end of a 60 minute spontaneous breathing trial
- Secondary Outcome Measures
Name Time Method ength of hospital stay. <br/ ><br>Timepoint: total duration of stay in hospital