A clinical trial to predict non invasive ventilation failure in chronic obstructive pulmonary disease patients using ultrasonographic evaluation of diaphragm
Not Applicable
- Conditions
- Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
- Registration Number
- CTRI/2023/03/050196
- Lead Sponsor
- Dr Kanika Chaudhary
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
COPD patients of either gender having a respiratory rate > 30 breaths per minute, peripheral oxygen saturation (SpO2) <88% with oxygen therapy through a Venturi mask or Non-Rebreathing Mask and active use of accessory muscles of respiration or paradoxical abdominal breathing.
Exclusion Criteria
1)Refusal of written informed consent
2)Mentally Retarded patients
3)Shock requiring vasopressors support
4)Acute pulmonary edema
5)Interstitial lung disease
6)Chest wall deformities
7)Previous diaphragmatic palsy
8)Papilledema
9)Pregnancy
10)Obesity (BMI >35 Kg/m2)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To predict NIV failure <br/ ><br>Timepoint: Assessment will be done at baseline,6,12 and 24 hours of NIV treatment
- Secondary Outcome Measures
Name Time Method ICU stay, hospital stay and in hospital mortality <br/ ><br>Timepoint: Secondary outcome will be assessed till 1 month of hospital stay