Effectiveness of diaphragmatic ultrasound as a predictor of successful weaning from mechanical ventilatio

Not Applicable

Recruiting

• Conditions: Respiratory

• Registration Number: PACTR202408823933769
• Lead Sponsor: no

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1-Adult patients, aged between 18 to 65 years.
2-Patient who are mechanically ventilated more than 48 hours and meet all the following criteria for spontaneous breathing trial:
•Resolution or improvement of the disease leading to MV,
•adequate oxygenation indicated by arterial oxygen saturation (SaO2)>90% with inspired oxygen fraction (FiO2) =0.5, or arterial oxygen partial pressure to inspired oxygen fraction (PaO2/FiO2)=150 mmHg, both with positive end-expiratory pressure (PEEP)=8 cmH2O,
•respiratory rate=30 breaths/min,
• intact cough reflex
•hemodynamic stability in low dose or absence of vasopressors.

Exclusion Criteria

1-Pregnancy
2-Thoracostomy or pneumothorax
3-Flail chest or rib fracture
4-Neuromuscular disease
5-Diaphragmatic paralysis
6-Cerebrovascular stroke with bulbar symptoms

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome: To determine the predictive value of diaphragmatic rapid shallow breathing indices in successful weaning from the ventilator.

Secondary Outcome Measures

Name	Time	Method
Secondary outcome: Correlation between the diaphragmatic indices and days of invasive mechanical ventilation, length of stay in the ICU and ICU mortality.