Mechanisms by which fruit and vegetables influence postmenopausal bone health: a randomised controlled trial in a well-characterised populatio

Completed

• Conditions: ow bone mass/risk of osteoporosis; Musculoskeletal Diseases; Osteoporosis

• Registration Number: ISRCTN86186352
• Lead Sponsor: Food Standards Agency (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 260

Inclusion Criteria

Women aged 55 years to 65 years who had taken part in a longitudinal study (Aberdeen Prospective Osteoporosis Screening Study). Includes:
1. Otherwise healthy women taking other types of diuretics (not potassium sparing diuretics) or hypertension tablets
2. Women on thyroxine treatment provided their thyroid function is stable (as assessed by free Thyroxine [T4] and Thyroid Stimulating Hormone [TSH] levels) and their dose had not changed in the year prior to study entry

Exclusion Criteria

1. Suffering from severe disease
2. Malabsorption
3. Having difficulties swallowing tablets/capsules
4. Taking oral corticosteroids
5. On or past bisphosphonate treatment (more than a few weeks)
6. Taking Hormone Replacement Therapy (HRT) in the last six months
7. Less than five years past the menopause
8. Currently taking potassium-sparing diuretics
9. Osteoporosis diagnosed from Dual Energy X-ray Absorptiometry (DEXA) scan at baseline visit

Study & Design

• Study Type: Interventional
• Study Design: Not specified