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Curative Effect of Guilu Erxian Gum on Primary Osteoporosis of Yin Yang Deficiency Syndrome

Phase 1
Conditions
osteoporosis
Registration Number
ITMCTR2200006736
Lead Sponsor
Qingdao Hospital of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Comply with the diagnostic criteria of Western medicine and TCM for osteoporosis;
2. Male or female, age 50-85, female natural menopause for more than 1 year;
3. The patient signed the informed consent form, was willing to accept the examination and treatment, and was able to cooperate with the follow-up.

Exclusion Criteria

(1) Various types of metabolic bone diseases, such as osteogenesis imperfecta, osteomalacia, Cushing's syndrome, hyperprolactinemia, thyroid or parathyroid diseases, etc;
(2) Secondary osteoporosis, or disuse osteoporosis caused by limb deformity and disability;
(3) Patients with other serious diseases, such as brain, heart, lung, liver, kidney and hematopoietic system;
(4) Those who take drugs that affect bone metabolism or have received medical treatment for osteoporosis within 12 months;
(5) Those who are allergic to the study drug;

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
IL-18;IL-1ß;NLRP3;Caspase-1;bone density;TCM clinical symptoms;
Secondary Outcome Measures
NameTimeMethod
renal function;Pain score;MDA;NO;liver function;Bone metabolism index;
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