Effect of Wuda granules on the recovery of gastrointestinal function after bowel resection: study protocol for a randomized controlled pilot trial
- Conditions
- Bowel cancer
- Registration Number
- ITMCTR2000003926
- Lead Sponsor
- Guangdong Provincial Hospital of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Patients who have undergone laparoscopic BR;
(2) Aged 18 years or older;
(3) surgery time,3 to 4.5 hours;
(4) anesthesia time,3.5 to 5 hours;
(5) TCM syndrome type, Qi deficiency and Qi stagnation;
(6) willingness to provide written informed consent.
(1) Advanced malignant tumor cachexia, extreme weakness;
(2) malignant tumors requiring extended radical surgery or enterostomy;
(3) cardiovascular, liver, kidney, brain, or lung co-morbidity, or other serious diseases;
(4) poorly controlled hypertension or diabetes;
(5) mental illness;
(6) allergy to the intervention;
(7) pregnant or breast-feeding women;
(8) severe malnutrition (serum albumin < 21 g/L, pre-albumin < 0.1 g/L);
(9) repeated abdominal surgery and severe intestinal adhesions;
(10) blood loss > 400 mL during surgery, need blood transfusion during or after surgery;
(11) serious complications occurring within 6 h after surgery (e.g., multiple organ dysfunction);
(12) emergency surgery;
(13) must use drugs or treatments that have a significant impact on gastrointestinal function after surgery;
(14) currently participating in other clinical trials, or having participated in another clinical study in the previous month;
(15) participants considered inappropriate to participate the study by clinical investigators.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method first toleration of solid food;time for first defecation;
- Secondary Outcome Measures
Name Time Method Postoperative ileus -related morbidity;time to discharge order written;time to first flatus;postoperative length of stay;