study to see the effect of oral pregabalin if given before laparoscopic cholecystectomy surgery on pain occurring after surgery and the need for additional analgesic

Not yet recruiting

• Conditions: Calculus of gallbladder without cholecystitis, (2) ICD-10 Condition: K802||Calculus of gallbladder without cholecystitis,

• Registration Number: CTRI/2023/05/053222
• Lead Sponsor: Mahatma Gandhi Medical College Hospital Jaipur

Brief Summary

Laproscopic cholecystectomy is one of common surgical procedure, however post operative pain associated with it remains a major challenge. Post operative pain has been treated with many classes of drug available, but they have wide range of side effects.

This study is aimed to evaluate the effectiveness of oral pregabalin on post operative pain intensity and analgesic requirement.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-05-28
• Study Start: 2023-07-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1.American Society of Anesthesiologists (ASA) I and II patients.
• 2.Age group of 18-65 years.
• 3.Patient with written valid consent.
• 4.Patient undergoing elective laparoscopic cholecystectomy.

Exclusion Criteria

• 1.Patient refusal to participate in study.
• 2.History of allergy to study drug.
• 3.Pregnant and Lactating women.
• 4.Patient with impaired liver or kidney function.
• 5.History of chronic pain or daily intake of analgesics.
• • History of chronic use of central nervous system depressant drugs and anti-convulsant.
• • Morbidly obese.
• • Inability to comprehend or participate in pain scoring system.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the post operative pain intensity at rest and on movement.	0 hour | 8 hour | 16 hour | 24 hour
To assess total dose of rescue analgesia required in first 24 hours	0 hour | 8 hour | 16 hour | 24 hour

Secondary Outcome Measures

Name	Time	Method
to assess severity and side effects of drug	post operatively

Trial Locations

Locations (1)

Mahatma Gandhi Medical College; 🇮🇳 Jaipur, RAJASTHAN, India

Mahatma Gandhi Medical College

🇮🇳Jaipur, RAJASTHAN, India

Swati gupta

Principal investigator

9621103819

gupta.swati0922@gmail.com