NL-OMON47887已完成不适用
Translating neuroimaging findings from research into clinical practice (PSYSCAN): Clinical High Risk - PSYSCAN - UHR
Institute of Psychiatry, King's College, London0 个研究点目标入组 74 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 12 至 99（—）
入选标准
- •* 16-40 years old
- •* Written informed consent of subjects aged 18 to 40 years
- •* Written informed consent of parents and/or legal guardians for subjects aged
- •16 or 17, in
- •addition to assent from the minor subject, following local laws and regulations
- •Participants at high risk of psychosis will be evaluated using a quantitative
- •clinical tool that
- •* Inclusion into one of three groups as assessed by the Comprehensive
- •Assessment of At-Risk Mental States (CAARMS version 2006):
- •i) vulnerability group,
- •ii) attenuated psychosis group,
- •iii) brief intermittent psychosis symptoms group.
排除标准
- •* Any previous neurosurgery or neurological disorder, including epilepsy
- •* History of head injury resulting in unconsciousness lasting at least 1 hour
- •* Pregnancy
- •* Any contraindications for MRI
- •* Refusing to have blood drawn and/or MRI performed
- •* Subject is unable to fully comprehend the purpose of the study or make a
- •decision whether or not to participate
- •* Estimate of IQ < 70
- •* Antipsychotic medication for > 30 days (cumulative number of days) in the 3
- •before the baseline assessments (including self-ratings and screening
- •assessments), at
- •doses that would be adequate for treating a first episode of psychosis (i.e.
- •excludes very
- •* Any past episode of frank psychosis lasting > 7 days
研究者
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