NL-OMON47887
Completed
Not Applicable
Translating neuroimaging findings from research into clinical practice (PSYSCAN): Clinical High Risk - PSYSCAN - UHR
Institute of Psychiatry, King's College, London0 sites74 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- high risk of psychosis
- Sponsor
- Institute of Psychiatry, King's College, London
- Enrollment
- 74
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\* 16\-40 years old
- •\* Written informed consent of subjects aged 18 to 40 years
- •\* Written informed consent of parents and/or legal guardians for subjects aged
- •16 or 17, in
- •addition to assent from the minor subject, following local laws and regulations
- •Participants at high risk of psychosis will be evaluated using a quantitative
- •clinical tool that
- •\* Inclusion into one of three groups as assessed by the Comprehensive
- •Assessment of At\-Risk Mental States (CAARMS version 2006\):
- •i) vulnerability group,
Exclusion Criteria
- •\* Any previous neurosurgery or neurological disorder, including epilepsy
- •\* History of head injury resulting in unconsciousness lasting at least 1 hour
- •\* Pregnancy
- •\* Any contraindications for MRI
- •\* Refusing to have blood drawn and/or MRI performed
- •\* Subject is unable to fully comprehend the purpose of the study or make a
- •decision whether or not to participate
- •\* Estimate of IQ \< 70
- •\* Antipsychotic medication for \> 30 days (cumulative number of days) in the 3
- •before the baseline assessments (including self\-ratings and screening
Outcomes
Primary Outcomes
Not specified
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