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Clinical Trials/NCT02930486
NCT02930486
Completed
Not Applicable

Ziptight or Tricortical Screw Fixation of Acute Tibiofibular Syndesmotic Injury

Vestre Viken Hospital Trust1 site in 1 country120 target enrollmentJanuary 2016
ConditionsAnkle Fractures

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ankle Fractures
Sponsor
Vestre Viken Hospital Trust
Enrollment
120
Locations
1
Primary Endpoint
OTA Score (Modified American Orthopaedic Foot and Ankle Society ankle hind foot score)
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Treatment of syndesmotic injury with Weber C fracture. A randomized study comparing ZipTight suture endobutton and one tricortical 3,5 mm syndesmotic screw.

Detailed Description

Syndesmotic injuries are common and often associated with unstable ankle fractures. The most common treatment is with a syndesmotic screw through the fibula and tibia which is later removed, usually after 10-12 weeks. The ZipTight suture endobutton (Biomet) is used for the same indication. It does not need removal and thus avoids subsequent surgery. This trial will compare these two methods and see if they are equal. patients 18-70 years presenting to one of the three hospitals with and acute syndesmotic injury are eligible for inclusion. 120 patients are randomized to two treatment groups. One group will be treated with a ZipTight suture endobutton fixation and the other receives a tricortical screw fixation. Neither suture endobutton or screw is routinely removed. Follow up intervals are at 6 weeks, 6, 12 and 24 months with clinical and-points. Standardized CT scans are taken postoperatively and at 12 and 24 months.

Registry
clinicaltrials.gov
Start Date
January 2016
End Date
October 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18 to 70 years
  • Acute syndesmotic injury with Weber type C fracture

Exclusion Criteria

  • Prior injury og the same ankle
  • Severe injury of the same leg affecting rehabilitation
  • Symptomatic osteoarthritis of same ankle
  • open injury
  • Decubital injury affecting surgical site
  • Dementia or unable to sign informed consent
  • neuropatic conditions affecting same leg

Outcomes

Primary Outcomes

OTA Score (Modified American Orthopaedic Foot and Ankle Society ankle hind foot score)

Time Frame: 24 months

Modified American Orthopaedic Foot and Ankle Society ankle hind foot score (0-100)

Secondary Outcomes

  • Health-related quality of life (EQ-5D)(24 months)
  • Manchester-Oxford Foot questionnaire (MOxFQ)(24 months)
  • VAS(24 months)
  • Dorsiflexion angle(24 months)
  • CT measurements of syndesmotic distance(24 months)

Study Sites (1)

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