Contrast-enhanced ultrasound and magnetic resonance imaging for the evaluation of neovascularisation in carotid artery plaques

Completed

• Conditions: arteriosclerosis; Atherosclerosis; 10003216

• Registration Number: NL-OMON31966
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 18

Inclusion Criteria

-Subjects with a >70% carotid artery stenosis who are scheduled for carotid endarterectomy.
-Age 18 years or older

Exclusion Criteria

-Patients with acute coronary syndrome or clinically unstable ischaemic cardiac disease.
-Patients with right-to-left shunts, severe pulmonary hypertension, uncontrolled systemic hypertension, and adult respiratory distress syndrome.
-Pregnant and lactating women
-Patients with documented allergy to contrast media or a renal clearance <30 ml/minute
-Standard contra-indications for MRI (ferromagnetic implants like pacemakers or other electronic implants, metallic eye fragments, vascular clips, claustrophobia, etc).

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The accuracy of contrast-enhanced ultrasound and MRI in depicting<br /><br>neovascluarisation in a carotid artery plaque.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>