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Prevention of ICU-Related Anxiety in Lung Transplantation by Virtual Reality Therapy - PIRAT Study

Not Applicable
Conditions
Depression, Anxiety
Transplantation, Lung
PTSD
Interventions
Behavioral: Exposure therapy with Virtual Reality.
Registration Number
NCT05125406
Lead Sponsor
Assistance Publique Hopitaux De Marseille
Brief Summary

ICU patients frequently face complicated recovery processes, including long-term anxiety disorders. Lung transplantation (LTx) offers people with terminal respiratory conditions both the hope of prolonged survival and a better quality of life related to health. Among the disorders usually encountered in the postoperative period of LTx are anxio-depressive disorders. These anxiety disorders affect the quality of life related to health and compromise the follow-up of the patient by phenomenon of psychological disinvestment. Other psychological disorders are also anchored in the patient's experience of this post-surgical ICU period (ie, depressive episodes and/or, at a distance, post-traumatic stress disorder (PTSD). Various models of management of anxio-depressive disorders and PTSD are proposed in the literature. To our knowledge, while many of them have shown their efficiency in the curative management of disorders, few have demonstrated their effectiveness in preventing them. Exposure therapies using virtual reality (ETVR) have in the past demonstrated their effectiveness in many areas of psychiatry. In our study, experimental arm patients will be offered ETRV support with a virtual reality headset. A scenario with progressively increasing stress levels linked to the ICU environment and different situational contexts (alarms, etc.) will be presented to patients. This habituation to the potentially anxiety context of ICU will reduce the occurrence of psycho-cognitive disorders by progressive extinction phenomenon.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Age above 18 years
  • Registration on the lung transplant waiting list
  • Signature of consent
Exclusion Criteria
  • Minor patient, pregnant or breastfeeding woman, or not affiliated to the social security scheme
  • Patient under guardianship or curatorship
  • Patient with a history of mental illness
  • Patient not mastering the French language
  • Patient deprived of liberty
  • Patient carrying a transplanted organ (liver, kidney, heart ...)
  • Lung re-transplantation

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Exposure therapy using Virtual Reality (ETVR)Exposure therapy with Virtual Reality.-
Primary Outcome Measures
NameTimeMethod
Spielberger state trait anxiety inventory for adults3 months post lung transplantation

The State-Trait Anxiety Inventory (STAI) has been used extensively in research and clinical practice. It comprises separate self-report scales for measuring state and trait anxiety. The S-Anxiety scale (STAI Form Y-1) consists of twenty statements that evaluate how respondents feel "right now, at this moment." The T-Anxiety scale (STAI Form Y-2) consists of twenty statements that assess how people generally feel.

Secondary Outcome Measures
NameTimeMethod
Post-traumatic stress disorder Checklist Scale (PCLS)3 and 6 months post lung transplantation

The IES-R is a solid measure of post-trauma phenomena and Posttraumatic Stress Disorder.

The Impact of Event Scale -Revised3 and 6 months post lung transplantation

The IES-R is a solid measure of post-trauma phenomena and Posttraumatic Stress Disorder.

Hospital Anxiety and Depression scale (HADS)3 and 6 months post lung transplantation

The Hospital Anxiety and Depression Scale (HADS) measure anxiety and depression in a general medical population of patients.

Trial Locations

Locations (1)

Assistance Publique Des Hôpitaux de Marseille

🇫🇷

Marseille, France

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