Cohorte Nationale VIH-2
- Conditions
- HIV-2 Infection
- Registration Number
- NCT04658329
- Lead Sponsor
- ANRS, Emerging Infectious Diseases
- Brief Summary
The HIV2 study is an open cohort of prospective, multicentric, national observation. The main objective is to study HIV-2 infection in adult patients followed in France.
- Detailed Description
The secondary objectives are :
* Describe the epidemiological and clinical characteristics of participants infected with HIV-2, and the immuno-virological characteristics of the infection.
* To study the clinical and immunological progression of HIV-2 infection and the prognostic factors of this evolution.
* Study the response to antiretroviral treatment (clinical, immuno-virological) and contribute to the identification of the antiretroviral strategies and combinations most suited to the particularities of the infection.
* Allow an evaluation of the care practices of participants followed in French hospitals
* Provide a bank of clinical-biological data and samples allowing the performance of virological and / or immunological studies on HIV-2 infection.
The follow-up of the participants is different according to the therapeutic status of the participants, naive of antiretroviral treatment or already treated with antiretrovirals.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1185
- HIV-2 infection only, diagnosed by ELISA, confirmed by Western-Blot test,
- Follow-up in consultation or hospitalization in one of the investigating centers,
- Age greater than or equal to 18 years,
- Prolonged follow-up possible, residence in France planned for at least one year,
- Consent to participate,
- Long-term medical care possible for the participant, or by medical aid (AME), or declaration of obtaining AME at the time of inclusion.
- HIV-1 infection
- Double HIV-1 + HIV-2 seropositivity
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Study HIV-2 infection rate in adult patients followed in France At the baseline
- Secondary Outcome Measures
Name Time Method Pourcentage of response to antiretroviral treatment evaluate by serology samples Up to 25 years Pourcentage of good management practices of patients followed in French hospitals evaluate by results Up to 25 years During the procedure
The epidemiological parameters and progression of patients infected with HIV-2 evaluate by a questionnaire Up to 25 years Every 6 months
Pourcentage of patient with HIV-2 Up to 25 years The prognostic factors of patient evolution are evaluate by biological samples
The clinical progression of patients infected HIV-2 evaluate by samples: biological examinations Up to 25 years Every 6 months
The rate of immuno-virological charge of the infection evaluate by serology samples Up to 25 years Every 6 months
Trial Locations
- Locations (29)
Centre Hospitalier Fran莽ois Quesnay
馃嚝馃嚪Mantes la Jolie, France
H么pital Saint Andr茅
馃嚝馃嚪Bordeaux, France
Service de Medecine Interne Hopital Antoine Beclere
馃嚝馃嚪Clamart, France
H么pital Louis Mourier
馃嚝馃嚪Colombes, France
H么pital de l'Hotel Dieu
馃嚝馃嚪Nantes, France
H么pital de La Croix Rousse
馃嚝馃嚪Lyon, France
Avicenne
馃嚝馃嚪Bobigny, France
H么pital Sud Francilien
馃嚝馃嚪Corbeil-essonnes, France
Centre hospitalier Victor Dupouy
馃嚝馃嚪Argenteuil, France
H么pital Henri Mondor
馃嚝馃嚪Creteil, France
H么pital Lariboisi猫re
馃嚝馃嚪Paris, France
Centre Hospitalier Ren茅 Dubos
馃嚝馃嚪Pontoise, France
H么pital Saint Antoine
馃嚝馃嚪Paris, France
H么pital Tenon
馃嚝馃嚪Paris, France
H么pital Gui de Chaudiac
馃嚝馃嚪Montpellier, France
Service de Medecine Interne Hopital Cochin
馃嚝馃嚪Paris, France
H么pital H么tel Dieu
馃嚝馃嚪Paris, France
CHI Poissy Saint Germain en Laye
馃嚝馃嚪Saint Germain en Laye, France
CHI Villeneuve Saint Georges
馃嚝馃嚪Villeneuve Saint Georges, France
H么pital la Piti茅 Salp茅tri猫re
馃嚝馃嚪Paris, France
Service de M茅decine interne - Centre Hospitalier Intercommunal
馃嚝馃嚪Cr茅teil, France
H么pital Edouard Herriot
馃嚝馃嚪Lyon, France
H么pital Saint Louis
馃嚝馃嚪Paris, France
H么pital Bichat - Claude Bernard
馃嚝馃嚪Paris, France
H么pital Andr茅 Mignot
馃嚝馃嚪Versailles, France
Hopital du Kremlin Bic锚tre Service de m茅decine interne
馃嚝馃嚪Paris, France
H么pital Delafontaine
馃嚝馃嚪Saint-Denis, France
H么pital Bretonneau - Service des Maladies Infectieuses
馃嚝馃嚪Tours, France
H么pital Pontchaillou
馃嚝馃嚪Rennes, France