Cohorte Nationale VIH-2
- Conditions
- HIV-2 Infection
- Registration Number
- NCT04658329
- Lead Sponsor
- ANRS, Emerging Infectious Diseases
- Brief Summary
The HIV2 study is an open cohort of prospective, multicentric, national observation. The main objective is to study HIV-2 infection in adult patients followed in France.
- Detailed Description
The secondary objectives are :
* Describe the epidemiological and clinical characteristics of participants infected with HIV-2, and the immuno-virological characteristics of the infection.
* To study the clinical and immunological progression of HIV-2 infection and the prognostic factors of this evolution.
* Study the response to antiretroviral treatment (clinical, immuno-virological) and contribute to the identification of the antiretroviral strategies and combinations most suited to the particularities of the infection.
* Allow an evaluation of the care practices of participants followed in French hospitals
* Provide a bank of clinical-biological data and samples allowing the performance of virological and / or immunological studies on HIV-2 infection.
The follow-up of the participants is different according to the therapeutic status of the participants, naive of antiretroviral treatment or already treated with antiretrovirals.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1185
- HIV-2 infection only, diagnosed by ELISA, confirmed by Western-Blot test,
- Follow-up in consultation or hospitalization in one of the investigating centers,
- Age greater than or equal to 18 years,
- Prolonged follow-up possible, residence in France planned for at least one year,
- Consent to participate,
- Long-term medical care possible for the participant, or by medical aid (AME), or declaration of obtaining AME at the time of inclusion.
- HIV-1 infection
- Double HIV-1 + HIV-2 seropositivity
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Study HIV-2 infection rate in adult patients followed in France At the baseline
- Secondary Outcome Measures
Name Time Method Pourcentage of response to antiretroviral treatment evaluate by serology samples Up to 25 years Pourcentage of good management practices of patients followed in French hospitals evaluate by results Up to 25 years During the procedure
The epidemiological parameters and progression of patients infected with HIV-2 evaluate by a questionnaire Up to 25 years Every 6 months
Pourcentage of patient with HIV-2 Up to 25 years The prognostic factors of patient evolution are evaluate by biological samples
The clinical progression of patients infected HIV-2 evaluate by samples: biological examinations Up to 25 years Every 6 months
The rate of immuno-virological charge of the infection evaluate by serology samples Up to 25 years Every 6 months
Trial Locations
- Locations (29)
Centre Hospitalier François Quesnay
🇫🇷Mantes la Jolie, France
Hôpital Saint André
🇫🇷Bordeaux, France
Service de Medecine Interne Hopital Antoine Beclere
🇫🇷Clamart, France
Hôpital Louis Mourier
🇫🇷Colombes, France
Hôpital de l'Hotel Dieu
🇫🇷Nantes, France
Hôpital de La Croix Rousse
🇫🇷Lyon, France
Avicenne
🇫🇷Bobigny, France
Hôpital Sud Francilien
🇫🇷Corbeil-essonnes, France
Centre hospitalier Victor Dupouy
🇫🇷Argenteuil, France
Hôpital Henri Mondor
🇫🇷Creteil, France
Hôpital Lariboisière
🇫🇷Paris, France
Centre Hospitalier René Dubos
🇫🇷Pontoise, France
Hôpital Saint Antoine
🇫🇷Paris, France
Hôpital Tenon
🇫🇷Paris, France
Hôpital Gui de Chaudiac
🇫🇷Montpellier, France
Service de Medecine Interne Hopital Cochin
🇫🇷Paris, France
Hôpital Hôtel Dieu
🇫🇷Paris, France
CHI Poissy Saint Germain en Laye
🇫🇷Saint Germain en Laye, France
CHI Villeneuve Saint Georges
🇫🇷Villeneuve Saint Georges, France
Hôpital la Pitié Salpétrière
🇫🇷Paris, France
Service de Médecine interne - Centre Hospitalier Intercommunal
🇫🇷Créteil, France
Hôpital Edouard Herriot
🇫🇷Lyon, France
Hôpital Saint Louis
🇫🇷Paris, France
Hôpital Bichat - Claude Bernard
🇫🇷Paris, France
Hôpital André Mignot
🇫🇷Versailles, France
Hopital du Kremlin Bicêtre Service de médecine interne
🇫🇷Paris, France
Hôpital Delafontaine
🇫🇷Saint-Denis, France
Hôpital Bretonneau - Service des Maladies Infectieuses
🇫🇷Tours, France
Hôpital Pontchaillou
🇫🇷Rennes, France