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The Effects of Non-Surgical Periodontal Therapy on Neutrophil Elastase and Elastase alpha-1 Proteinase Inhibitor Levels in GCF in Periodontitis Patients with or without Acute Coronary Syndrome

Not Applicable
Completed
Conditions
Acute coronary syndrome (ACS) is the common term used to describe the clinical signs and symptoms myocardial ischemia&#44
unstable angina&#44
non&#45
segmental elevation of myocardial infarction and segment ele
Non&#45
Surgical Periodontal Therapy&#44
Neutrophil Elastase&#44
Elastase alpha&#45
1 Proteinase Inhibitor
Acute Coronary Syndrome&#44
Registration Number
TCTR20200402001
Lead Sponsor
Selcuk University Scientific Research Projects
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
39
Inclusion Criteria

The periodontal condition was graded as follows on the basis of the current classification method for periodontal diseases localized or generalized periodontitis of stage II or stage III with grade B or grade C.

Exclusion Criteria

Exclusions for both groups included metabolic disorders, high blood pressure, treated with antihypertensive medications, and periodontal therapy and antibiotic treatment 3 months prior the study. Smoking habits, education status were also recorded.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
GCF NE-α1PI activity baseline-1-month and 3-month after therapy picogram
Secondary Outcome Measures
NameTimeMethod
CRP baseline-1-month and 3-month after therapy mg
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