Association between joint pain and gum diseases

Phase 2

Completed

• Conditions: Health Condition 1: - Health Condition 2: null- Rheumatoid arthritis patients treated as Out patients in Department of Rheumatology, Madras Medical College suffering from chronic periodontitisHealth Condition 3: M056- Rheumatoid arthritis with involvement of other organs and systemsHealth Condition 4: M056- Rheumatoid arthritis with involvement of other organs and systemsHealth Condition 5: M059- Rheumatoid arthritis with rheumatoid factor, unspecified

• Registration Number: CTRI/2016/03/006751
• Lead Sponsor: Institute of RheumatologyMadras Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1. Patients willing for voluntary participation and have signed informed consent.

2. Age group: 30- 65 years old.

3. Either sex.

4. under medication for rheumatoid arthritis

Patients taking DMARD- disease modifying anti-rheumatic drugs for atleast 6 months

5. Having atleast 8 teeth

6. Periodontal disease (at least 1 site with PPD >4mm, clinical attachment loss > 3mm)

7. Available for the study for a period of 6 months

Exclusion Criteria

1. Recent history of hospitalization.

2. Acute generalized infection/chronic systemic infection necessitating chronic antibiotic intake.

3. Acute oral infection or condition necessitating extraction/suspected premalignant lesions/conditions in the mouth

4. Patients with uncontrolled, Hypertension, Cardiovascular, Respiratory, Renal disorder.

5. Patients in need of any change or increase in dosage of DMARD drugs.

6. Patients with diabetes mellitus, psoriatic arthritis, ankylosing spondylitis

7. Current smokers

8. Pregnancy or lactation at the time of inclusion.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in DAS 28 Disease Activity Score in Rheumatoid patients with Chronic periodontitisTimepoint: 3 months

Secondary Outcome Measures

Name	Time	Method
Quality of Life Index (QOLI) in rheumatoid arthritis patientsTimepoint: 3 months