JPRN-UMIN000012493
Completed
未知
Investigation of clinical efficacy of aflicbercept in patients with polypoidal choroidal vasculopathy (PCV) with resistance of ranibizumab - Investigation of aflivercept for PCV with resistance of ranibizumab
Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo0 sites30 target enrollmentDecember 4, 2013
ConditionsPolypoidal choroidal vasculopathy
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Polypoidal choroidal vasculopathy
- Sponsor
- Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Greatest Linear Dimension (GLD) of the total lesion area \<12 Macular Photocoagulation Study Disc Areas 2\) Presence of subretinal hemorrhage, scar or macular fibrosis (\>50% lesion area) 3\) Prior treatment with dexamethasone (\<6 months) or triamcinolone (\<30 days), intraocular surgery (\<6 months) 4\) Active intraocular inflammation 5\) Hypersensitivity or allergy to fluorescein or indocyanine green, clinically significant drug allergy or known hypersensitivity to therapeutic or diagnostic protein products 6\) pregnant women and nursing mothers 7\) Patient who the doctor in charge judges are ineligible for the study 8\) RPE tear or stage3 full\-thickness macular hole in the studied eye. 9\) Intraocular surgery (including cataract surgery, vitrectomy and subretinal surgery) in the studied eye within 6months.
Outcomes
Primary Outcomes
Not specified
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